As seen from the Williamsburg Bridge, peaking out from under some graf, is this advertisement for the New York Frame and Picture Co.
The company was founded in 1894 by Charles Horowitz and operated out of Fulton Street downtown.
Apparently, Mr. Horowitz was quite keen on plastering advertisements for his framing business all over town.
The website 14to42 has this shot from 3rd Ave and 21st
helpfully placed for max visibility from riders on the 3rd Ave El.
Horowitz apparently also ran one of the first ads in the New York Telephone Directory
Life wasn't all about fine upstanding business life for the Horowitz clan, however.
A 1912 article in the Times details how the family paid someone to torch their Fulton Street storefront for $55 in order to collect on the insurance money.
The company survived until the mid 1990's in their home on John Street, and achieved fame in the frame and picture world for providing the framing for those gold and platinum records that the RIAA hands out when a half million or a million record sales are reached
---David Freedlander